Descrição do Produto
Condroton Plus | Equine Joint Regenerator | 500 Grams - Vetnil
The synovial joint is composed of bony surfaces made up of uniform layers of hyaline cartilage, lubricated by a viscous synovial fluid, grouped and supported by the joint capsule.
Articular cartilage is made up of cells called chondrocytes, which synthesize and deposit around themselves a matrix that represents more than 90% of the total volume of the tissue. The cartilage matrix is composed of collagen fibers, proteoglycans and water.
This tissue plays an important role in joint function, helping to cushion mechanical shocks between the surfaces of the bone ends and promoting smooth, regular sliding with little friction between these surfaces.
Proteoglycans are molecules composed mainly of a central protein with glycosaminoglycan side chains (GAGs), which bind to hyaluronic acid through proteins, forming aggregates. The main glycosaminoglycan component of proteoglycans is Chondroitin.
The molecular structure of the cartilaginous matrix appears to be a fundamental part of adapting these tissues to compression. The high water retention in this tissue creates a cushioning effect similar to a sponge.
Cartilage degeneration leads to the loss of glycosaminoglycan chains with a consequent decrease in the function of this structure.
Chondroitin Sulfate and Glucosamine have a tropism for joint and cartilage tissues, where they selectively bind to damaged or damaged cartilage, initiating the regeneration process of this tissue. The use of glycosaminoglycans aims to replace what was lost during pathological processes (chondro-repair) and what is lost during the animal's normal activity (chondro-protection).
Another important property is the anti-inflammatory effect, noted after using these compounds.
Other physiological effects of chondroitin sulfate include: contributing to bone ossification and calcification, as well as maintaining the elasticity of tendons and ligaments. Additionally, an important anti-inflammatory effect is noted after the use of these compounds, resulting in the suppression of the release of inflammatory mediators, which reduces pain and joint effusion.
Glycosaminoglycans also inhibit the action of lysosomal enzymes (released by leukocytes into the synovial fluid), restore the permeability balance of the synovial membrane (rebuilding its mesh) and induce the production of sodium hyaluronate, increasing the lubricating effect between the articular cartilages. An important stimulating action on collagen synthesis was observed after the use of glycosaminoglycans with a low degree of sulfation.
Perna canaliculus is a marine mollusk rich in glycosaminoglycan precursors and hyaluronic acid, and also has mild anti-inflammatory activity. Its extract is obtained by dehydration and then ground.
Collagen is rich in free amino acids and is a biological source for the formation of proteoglycans. It is also part of articular cartilage.
Manganese acts as a coenzyme that polymerizes monomers to form glycosaminoglycans. Adequate levels of this coenzyme are necessary for optimal utilization of Glucosamine and Chondroitin Sulfate by the joint. Manganese deficiency leads to a decrease in Hyaluronic Acid, Chondroitin Sulfate and Heparin in the cartilage.
